Publications

The American journal of psychiatry. 2026-02-18; appiajp20250259.

Divergent Patterns of Genetic Overlap Between Severe Mental Disorders and Metabolic Markers

van der Meer D, Shadrin AA, Stinson SE, Koch E, Rokicki J, Rahman Z, Bergstedt J, Ottas A, Sønderby IE, Rødevand L, Fuhrer J, Quintana DS, Dale AM, O'Connell KS, Djurovic S, Lehto K, Milani L, Alver M, Andreassen OA

PMID: 41703690

Abstract

Bipolar disorder, major depressive disorder (MDD), and schizophrenia are severe mental disorders and are each associated with poor cardiometabolic health. Mapping genetic relationships of these heritable disorders with blood markers of metabolic activity may uncover biological pathways underlying this important shared clinical feature.

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