Haft DH, Selengut JD, Brinkac LM, Zafar N, White O
Genome Properties: a system for the investigation of prokaryotic genetic content for microbiology, genome annotation and comparative genomics.
Bioinformatics (Oxford, England). 2005-02-01; 21.3: 293-306.
The presence or absence of metabolic pathways and structures provide a context that makes protein annotation far more reliable. Compiling such information across microbial genomes improves the functional classification of proteins and provides a valuable resource for comparative genomics.