Publications

13-Jan-2016

Chen CJ, Ermler ME, Tan GS, Krammer F, Palese P, Hai R

Influenza A Viruses Expressing Intra- or Intergroup Chimeric Hemagglutinins.

Journal of virology. 2016-01-13; 90.7: 3789-93.

A panel of influenza A viruses expressing chimeric hemagglutinins (cHA) with intragroup or intergroup head/stalk combinations was generated. Viruses were characterized for growth kinetics and preservation of stalk epitopes. With a few notable exceptions, cHA viruses behaved similarly to wild-type viruses and maintained stalk epitopes, which indicated their potential as vaccine candidates to induce stalk-specific antibodies.

PMID: 26764009

This publication is listed for reference purposes only. It may be included to present a more complete view of a JCVI employee's body of work, or as a reference to a JCVI sponsored project.