PanOCT, Pan-genome Ortholog Clustering Tool, is a program written in PERL for pan-genomic analysis of closely related prokaryotic species or strains. Unlike traditional graph-based ortholog detection programs, it uses micro synteny or conserved gene neighborhood (CGN) in addition to homology to accurately place proteins into orthologous clusters.


Large-Scale Comparative Analysis of Microbial Pan-genomes using PanOCT.
Bioinformatics (Oxford, England). 2018-08-25;
PMID: 30165579
PanOCT: automated clustering of orthologs using conserved gene neighborhood for pan-genomic analysis of bacterial strains and closely related species.
Nucleic acids research. 2012-12-01; 40.22: e172.
PMID: 22904089