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Derrick Fouts is a Professor at the Rockville Campus. Dr. Fouts has extensive experience in viral and bacteriophage genomics, bacterial genomics, comparative genomics, and metagenomics of bacterial and viral communities.
Since joining Dr. Karen Nelson's group at TIGR/JCVI in 2001, Dr. Fouts has led several microbial sequencing projects, including animal, plant and human pathogens. Many of these projects were among the first to compare multiple strains. In addition to leading projects, Dr. Fouts has developed various software tools, including applications to perform multi-genome comparisons and heuristic software (Phage Finder) to identify prophage regions in bacterial genomes. He is currently leading the effort to sequence the human virome and reference viral and bacteriophage genomes as part of the NIH sponsored, Human Microbiome Project.
Dr. Fouts received his B.S. degree (1992) in Biology with honors from Indiana University, Bloomington, and his M.S. (1994) and Ph.D. (1997) degrees in Microbiology from the University of Illinois Urbana/Champaign Department of Microbiology. In 1997, he began postdoctoral work in Dr. Alan Collmer's lab at Cornell University.
Publications
Multidrug-Resistant Klebsiella pneumoniae from Pediatric Sepsis Patients in Nigeria
LOCUST
A custom sequence locus typer for classifying microbial genotypic and phenotypic attributes.
PanOCT
PanOCT is a program written in PERL for pan-genomic analysis of closely related prokaryotic species or strains.
Phage_Finder
Phage_Finder is a heuristic computer program written in PERL to identify prophage regions within bacterial genomes.
Genomics of Non-Tuberculosis Mycobacteria
GGRaSP
An R-package for selecting representative genomes using Gaussian mixture models.
PanACEA
PanACEA is a tool for Pan-Genome visualization, which utilizes locally-computed interactive web-pages to view ordered pan-genome data.
CRACKLE: Carbapenems in Klebsiella pneumoniae and Other Enterobacteriaceae
Designer Phage
Synthetic Engineering of Bacteriophage for Treatment of Wound InfectionsChronic Wound Microbiome
Bacterial Translocation and Changes in the Intestinal Microbiome in Mouse Models of Liver Disease
Genomic Analysis of Multidrug Resistance in Esbl-Positive and Carbapenem-Resistant Bacterial Pathogens
Influence of Genetic Variation and AMR in Enterobacter and E. coli Bloodstream Infections (BSI)
Genomics of Acinetobacter baumannii
Viral Synthetic Genomics to Engineer Large dsDNA Viruses
Rapid engineering of large dsDNA viruses using synthetic genomics assembly tools.
Genomics, Biomarkers and Mechanisms of Healing in Chronic Wounds
Utilize genomics approaches to identify the microbial composition and functional elements in non-healing and chronic wounds.
Antimicrobial Resistance from Combat Wounds
Asymptomatic Bacteriuria: Microbiome and Metaproteome
We use genomics approaches to detect the presence of bacteria with known inflammatory responses in asymptomatic patients.
Leptospira Genomics and Human Health
Signature Infiltration and Maintenance on Plasmid Elements creating a Forensic Microbial System (SIMPLE-FMS)
Genome Sequencing of Atypical Disease-associated and Emerging Infectious Disease Isolates of C. Jejuni, and Related Species
Vaginal Microbiome Project
A metagenomics approach to understanding the relationship between the vaginal microbiome, bacterial vaginosis, vaginal health and preterm birth.
Mouse Microbiome
Enteric dysbiosis associated with a mouse model of alcoholic liver disease. The translocation of bacteria and bacterial products into the circulation contributes to alcoholic liver disease.