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Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
TIGR investigators announced today that they have determined the complete genome sequence of a green-sulfur bacterium, Chlorobium tepidum
TIGR's new publication, the TIGR Triptych, features articles about Bacillus anthracis research and the new Pathogen Functional Genomics Resource Center
An Arabidopsis whole genome chip jointly developed by TIGR and Affymetrix Inc. has been completed and is now being tested
Scientists Find New Markers For Anthrax Isolates
In a pioneering use of genomics as a tool for the forensic analysis of microbes, TIGR scientists have found new genetic markers to distinguish the Bacillus anthracis isolate that was used in last fall's bioterror attack in Florida from closely related anthrax strains.
TIGR has partnered with MdBio, Inc. and the University of Maryland Biotechnology Institute (UMBI) to launch the MdBioLab in 2003
TIGR has partnered with MdBio, Inc. and the University of Maryland Biotechnology Institute (UMBI) to launch the MdBioLab in 2003, a mobile laboratory designed to enhance bioscience curricula for high school students and their teachers throughout the state of Maryland.
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The Search for Environmental “Gems” Continues
As an original crew member of the Sorcerer II circumnavigation that began in 2003, I had not been sailing/sampling on the boat since September 2007. I arrived in Florida with a mixture of emotions. Although life on board can be tedious, I was excited to return and embark on this next leg of...
Back on Land
We arrive in Ft. Lauderdale and are all glad to be back on land for a few days. But we were also elated by the success of the first part of the expedition. This first journey was difficult because we had to deploy and test new equipment, to sample a diverse array of environments and...
Through the Canal
We are now out in the warm and saline Caribbean Sea, and the waters are an intense blue. The waters are so blue, there is very little in them: we drop the CTD and barely get 0.25 micrograms of Chlorophyll per liter all the way to the 50 meter mark. The clear waters of the Caribbean are very...
Miraflores Locks
We passed through the gigantic Miraflores locks on the Pacific side of the Panama Canal this morning, and now we are in front of the Smithsonian Tropical Research Station on Lake Gatun. The Sorcerer has sampled here on two other occasions, so to continue our time course evaluation, we ready the...
Going Green to Blue
As we round the southern most point on our trip we notice that the water has gone from blue to green, and that there appear to be surface current and eddies in the water. We decide to stop and have a look with the CTD. As we lower the instrument from the aft cockpit, we encounter a layer of...
Costa Rican Dome
In Nicaraguan waters is a regular spring upwelling event sometimes referred to as the Costa Rican dome. Winds blow across the Central American Isthmus near Lake Nicaragua and contribute to an upwelling of nutrient rich waters. These nutrients enable phytoplankton to grow, and as we approach the...
Gulf of Tehuantepec
We spend the day transiting the famously capricious Gulf of Tehuantepec, but today winds were calm, and we were able to cut across the bay in good time. At the southern end of the gulf is an underwater seamount, so we maneuver the Sorcerer over the seamount in hopes of encountering an...
Acapulco Harbor, Mexico
There probably isn’t a harbor in Mexico more impacted by tourism and development than Acapulco. We pull into the stunningly beautiful harbor and sample in front of an area of high rise hotels. The depth of the spot we sampled is only 40 feet, so we just take a surface water sample. Of...
Sampling Blooms in Cabo Corrientes
Just south of Puerto Vallarta is Cabo Corrientes, and our satellite data indicate a large bloom extending 25 miles off the coast. As we enter the bloom the water turns an intense green, and there are numerous fish feeding in the area. Sampling conditions are ideal: bright sunshine, light...
Puerto Vallarta: Investigating the Influence of Coastal Development
Sampling today starts before sunrise when we arrive at Puerto Vallarta. In conjunction with our Mexican collaborators, we are investigating the influence of coastal development, particularly intensive tourism, on marine microbiota, so we take a sample of surface water in Banderas Bay and leave...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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