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Genome of Deadly Amoeba Shows Surprising Complexity; Study Reveals Evidence for Lateral Gene Transfer from Bacteria
The genome sequence of the parasitic amoeba Entamoeba histolytica, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly complex repertoire of sensory genes as well as a variety of bacterial-like genes that contribute to the organism's unique biology. TIGR scientists led the project, which presents the first genome-wide study of an amoeba. About 50 million people a year are infected by the parasite, which causes as many as 100,000 deaths annually.
Scientists Decipher Genome of a Fungus That Causes Life-Threatening Infections in Persons With Impaired Immunity
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Scientists Reveal Molecular Secrets of the Malaria Parasite
Groundbreaking Research Project May Help Boost Vaccine Development
Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
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JCVI Gala “2015: A Genome Odyssey” Celebrates Discovery
On October 24th, JCVI welcomed 200 guests to our third annual gala “2015: A Genome Odyssey.” Our annual gala has become a signature La Jolla event, and this year’s guests were not disappointed. Guests experienced an evening odyssey through land, sea and space interacting with JCVI...
June Grant Update
Congratulations to our JCVI Principal Investigators for the several successful grants that were awarded or that we received notification of in the month of June. All of the following PIs received official confirmation of awards to be made to them. Christopher Dupont, John Glass, Granger...
Q&A with Jessie J. Knight, Jr.
The JCVI CEO Council is a small group of distinguished men and women who are thought leaders in business, medicine, law, the arts and humanities, and community affairs. JCVI is fortunate to have individuals willing to serve as knowledgeable and enthusiastic ambassadors for our scientists and...
JCVI Scientist Tackles Global Sanitation Challenges
Orianna Bretschger received her B.S. in Physics and Astronomy at the University of Northern Arizona. After a five- year career in aerospace and consulting, she completed a PhD in Materials Science at the University of Southern California. Eager to focus her efforts on alternative energy...
Dr. Venter Delivers UCSD 2015 School of Medicine Commencement
Full text for the address follows. J. Craig Venter, PhD, UCSD , 2015 School of Medicine Commencement Address Chancellor Khosla, Dean Brenner, Dean Savoia, UC Regent Charlene Zettel, UC Regent Sheldon Engelhorn, invited guests, families and graduates, thank you for inviting me...
Johns Hopkins Announces Inaugural Recipient of Hamilton Smith Award for Innovative Research
JCVI's Hamilton O. Smith, MD has been recognized by Johns Hopkins University with a research award in his honor. The inaugural recipient of the award is Jie Xiao, an associate professor of biophysics and biophysical chemistry at the Johns Hopkins University School of Medicine. Dr....
Meet Richard Scheuermann, Ph.D., JCVI’s Director of Bioinformatics
Richard H. Scheuermann, Ph.D., who joined JCVI in 2012 from the University of Texas Southwestern as the Director of Bioinformatics, is an accomplished researcher and educator. He and his team apply their deep knowledge in molecular immunology and infectious disease to develop novel...
Zoo in You Exhibit Now Open
Did you know trillions of microbes make their homes inside your body? In fact, these microorganisms outnumber our human cells 10 to 1, “colonize” us right from birth, and are so interwoven into our existence that without each other, none of us would survive! Thanks to new sophisticated...
In Memory of Dr. J. Robert Beyster
The JCVI family mourns the loss of a true friend and generous supporter, Dr. J. Robert Beyster. Dr. Beyster was a World War II Veteran, a nuclear engineer whose research propelled the Department of Defense's weapons systems and submarines into the future of war fighting, but most notably,...
Science on the Sea Ice Edge
On Sunday, December 14th JCVI scientists Andy Allen, Erin Bertrand, and Jeff Hoffman flew to New Zealand to begin the arduous journey to the sea ice edge of Antarctica. The JCVI team was joined by three members of the University of Southern California, led by David Hutchins, and three members...
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Reflections on the 20th Anniversary of the First Publication of the Human Genome
A new wave of research is needed to make ample use of humanity’s “most wondrous map”
Scientists rush to determine if mutant strain of coronavirus will deepen pandemic
U.S. researchers have been slow to perform the genetic sequencing that will help clarify the situation
After saving countless lives, Nobel laureate Hamilton Smith retires as his own health falters
He has been a fixture in San Diego science for decades
The 'Wondrous Map': Charting of the Human Genome, 20 Years Later
Twenty years ago, President Bill Clinton announced completion of what was arguably one of the greatest advances of the modern era: the first draft sequence of the human genome.
Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
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