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Bioinformatics Resource Center at TIGR to Focus on Biothreat Pathogens
TIGR has signed a five-year, $21.1 million contract with the National Institute of Allergy and Infectious Diseases to establish and maintain a new national Bioinformatics Resource Center for the study of pathogens that are considered biothreat agents or are associated with emerging or re-emerging infectious diseases.
Anthrax Toxin Genes Found in Another Microbial Species
For the first time, researchers have found anthrax toxin genes in a naturally occurring microbe other than Bacillus anthracis, the bacterium that causes anthrax. The microbe that contains those anthrax genes is a strain of Bacillus cereus isolated from a patient with a medical condition similar to inhalation anthrax.
Decoding a Sulfate-Breathing Bug
Paving the way for better methods to protect pipelines and remediate metallic pollutants, TIGR scientists and collaborators have deciphered the genome of a sulfate-breathing bacterium, Desulfovibrio vulgaris, which can damage oil and natural gas pipelines and corrode oilfield equipment.
HP and TCAG Collaborate to Advance Medical and Environmental Genomic Discovery in Life Science
Scientists Decipher the Rat Genome
An international consortium of scientists that includes TIGR has completed a high-quality draft sequence of the rat genome. Comparing the rat to the human and mouse genomes, the Rat Genome Sequencing Project Consortium reported that nearly all human genes known to be associated with diseases have counterparts in the rat.
A New Spin on Spirochetes
Major Differences Found Between the Genomes of Oral Pathogen Treponema denticola and Related Spiral-Shaped Bacteria that Cause Syphilis and Lyme Disease
"Male-Targeting" Bacterium's Genome is Deciphered
Versatile Wolbachia has more mobile DNA than any other intracellular bacterium; Study may help in developing new treatments for diseases
IBEA Researchers Publish Results From Environmental Shotgun Sequencing of Sargasso Sea In Science; Discover 1,800 New Species And 1.2 Million New Genes, Including Nearly 800 New Photoreceptor Genes
IBEA Announces Sorcerer II Expedition, Global Expedition To Sample World's Oceans And Land To Characterize And Understand Microbial Populations Using Environmental DNA Sequencing
Gordon and Betty Moore Foundation give IBEA $4.25 Million Grant for Genomic Sequencing of DNA Samples from Expedition Discovery Channel to Film Expedition for TV Documentary
Discovery Channel to Film Expedition for TV Documentary
TIGR Offers International Travel Fellowships
Scientists Discover Way to Streamline Analysis of Maize Genome
Combination of Two Techniques Can Help Identify "Gene Islands" in the Key Crop
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Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs of...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in Howard...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to identify the...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after...
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be working...
Sequencing of high yield influenza reassortants at JCVI
As part of the Influenza Genome Sequencing Project, JCVI will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher’s lab has prepared the type A H3N2 high yield reassortants (hyrs) for the influenza...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming plans...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. JCVI Professor of Genomic Medicine,...
Summit on Systems Biology, June 15-17, 2011
I attended the Summit on Systems Biology hosted by Virginia Commonwealth University in Richmond, VA June 15-17. So, judging from the talks given, what is systems biology? Systems biology is non-linear and/or multi-step. Heavy math does not make something systems biology if it's...
Insights gained from influenza genomic sequence data: viral diversity within human populations
The advent of large amounts of influenza genomic sequence data produced by the Influenza Genome Sequencing Project (IGSP) has led to new concepts regarding influenza viral diversity. It was previously believed that a single influenza lineage entered a human population at the start of an...
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
Genetically modified bacteria-killing viruses used on patient for first time
Hair claimed to belong to Leonardo da Vinci to undergo DNA testing
Critics, however, argue that this effort is flawed from the beginning
Students learn about genomics, a life in science, at J. Craig Venter Institute
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