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Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium <em>Campylobacter</em> - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
J. Craig Venter Announces Consolidation of Three Research Organizations Into One New Not-For-Profit Organization — The J. Craig Venter Institute
The Center for Advancement of Genomics (TCAG), Institute for Biological Energy Alternatives (IBEA), and J. Craig Venter Science Foundation Joint Technology Center (JTC) consolidated to form J. Craig Venter Institute
Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
Scientists Explore Genome of Methane-breathing Microbe
First Complete DNA Sequence of a Methanotroph Reveals Metabolic Flexibility, Suggests Mechanisms for Increasing Its Usefulness For Biotechnology
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Italian Sampling Continues-Unique Animal in Italian Waters!
Wednesday July 14th Monday July 12th we woke up early and left the anchorage in Capraia Island. We arrived at Ischia island at 5:00 a.m. on Wednesday the 14th. In those 48 hours we collected 6 samples. Two samples were collected in the Northern Tyrrhenian Sea, two samples were collected over a...
Mediterranean Sampling Season Starts
Sunday July 11th 2010 On Thursday July 8th Sorcerer II set sail from Valencia Spain to start the Mediterranean season. Permits vary from country to country, Italy gave us 10 days to collect our samples, so we had to time our departure from Spain to fit our 10 day sampling window in Italy. As we...
The Sorcerer II Sampling Process
July 6th In the blog about the media event I posted a few days back I put a link to the JCVI media page. On this page you can learn about our research goals, funders and past expeditions (more links on the right side of the page). Before we set out for this sampling season I wanted to explain...
Valencia, The Home Of Sorcerer II And Crew Since September 2009
July 5th Valencia is located about 140 miles (365 kilometers) from Barcelona. Valencia has a rich history and a distinct culture from other Spanish cities. I have only spent a few months here, but I wanted to share some of the highlights with you all before we set sail and start our...
High-performance comparative metagenomics
Are your carrying out large scale metagenomics analyses to identify differences among multiple sample sites? Are you looking for suitable analysis tools? If you have not yet found the right analysis tool, you may be interested in the latest beta version of JCVI Metagenomics...
Media Day Circus On Sorcerer II
June 23nd On Monday June 21st we announced the official start of the Mediterranean leg of the Sorcerer II Global Ocean Sampling Expedition. Dr. Venter took time from his busy schedule to fly into Valencia and attend the event as well as representatives from The Life Technology Foundation. The...
Genomics of the Indoor Air Environment
Most of our life is spent in indoors, well-buffered from the constant changes in temperature, humidity, wind and light which shape life outside our homes and offices. It seems intuitive that the types of microorganisms which inhabit our indoor environment must be different from those on the...
Sorcerer II back at Sea!
June 13th 2010 After we collected and processed the sample from Blanes on May 26th we dropped off the collaborators on the dock, and set sail for France. After a overnight sail we reached our last Spanish sample site, it is in Spanish waters but monitored by French scientist. CTD Profile...
The Re-Sampling of Blanes By Karolina Ininbergs
May 26th 2010 After docking in Barcelona and picking up Jeff, who just finished the lake sampling with Chris up in the Pyrenees, we headed north-east towards Blanes Bay. We were also joined by Bea Diez, her PhD student Roy McKenzie, Meri Antó and Vanessa Balague from ICM, Barcelona. It was a...
BBMO — Blanes Bay Microbial Observatory
May 25th 2010 In 2008 I spent three months working at the Institute of Marine Sciences in Barcelona, hosted by Beatriz Diez in the Marine Microbiology group, headed by Carles Pedrós-Alió. One of the many microbial research projects at ICM is focused on environmental monitoring of marine...
A journey to the center of our cells
Biologists are discovering the true nature of cells—and learning to build their own.
Dr. Hend Alqaderi on paving the way for women in science in the GCC
Hend Alqaderi, a JCVI collaborator and mentee to Marcelo Freire receives the L’Oréal-Unesco Women in Science award
Leonardo Da Vinci: New family tree spans 21 generations, 690 years, finds 14 living male descendants
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
Genome Research Papers on Meningococcal Recombination, Psoriasis Variants in China, More
Sailing the Seas in Search of Microbes
Projects aimed at collecting big data about the ocean’s tiniest life forms continue to expand our view of the seas.
What the Public Should Not Know
J. Craig Venter, PhD, argues scientists have “a moral obligation to communicate what they're doing to the public,” and that more studies deserve greater public criticism.
Scientists coax cells with the world’s smallest genomes to reproduce normally
The discovery could sharpen scientists’ understanding of which functions are crucial for normal cells and what the many mysterious genes in these organisms are doing
San Diego arts, health, science and youth groups to share $71M from Prebys Foundation
The J. Craig Venter Institute is the recipient of three awards totaling more than $1.5M to study SARS-CoV-2 and heart disease
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