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Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
TIGR investigators announced today that they have determined the complete genome sequence of a green-sulfur bacterium, Chlorobium tepidum
TIGR's new publication, the TIGR Triptych, features articles about Bacillus anthracis research and the new Pathogen Functional Genomics Resource Center
An Arabidopsis whole genome chip jointly developed by TIGR and Affymetrix Inc. has been completed and is now being tested
Scientists Find New Markers For Anthrax Isolates
In a pioneering use of genomics as a tool for the forensic analysis of microbes, TIGR scientists have found new genetic markers to distinguish the Bacillus anthracis isolate that was used in last fall's bioterror attack in Florida from closely related anthrax strains.
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The dive: searching for deep ocean plastics in the Puerto Rico Trench
Editor’s note JCVI Staff Scientist Erin Garza, Ph.D., was selected to embark on a unique research expedition aboard the HOV Alvin submersible, a crewed deep-ocean research vessel owned by the United States Navy and operated by the Woods Hole Oceanographic Institution, that has brought...
Leg 1: headed to an unexplored area of the Puerto Rico Trench
Editor’s note JCVI Staff Scientist Erin Garza, Ph.D., was selected to embark on a unique research expedition aboard the HOV Alvin submersible, a crewed deep-ocean research vessel owned by the United States Navy and operated by the Woods Hole Oceanographic Institution, that has brought...
My journey begins: heading to the Puerto Rico Trench in search of deep-sea plastic
Editor’s note JCVI Staff Scientist Erin Garza, Ph.D., was selected to embark on a unique research expedition aboard the HOV Alvin submersible, a crewed deep-ocean research vessel owned by the United States Navy and operated by the Woods Hole Oceanographic Institution, that has brought...
Celebrating pioneers in science and medicine this Black History Month
Happy Black History Month! At JCVI, we believe in the importance of celebrating scientific trailblazers, particularly those who made groundbreaking advancements all while overcoming overt racism. Here, we have highlighted the stories and achievements of some of the most accomplished Black...
Eleven female scientists whose research changed the world
Today is Women’s Equality Day and to celebrate, we are highlighting accomplishments made by women in science and technology. While these scientists were influential in advancing their fields and championing the fair treatment of women in science, currently women only make up 28% of the...
Complete Genome Sequence of Strain JB001, a Member of Saccharibacteria Clade G6
The complexity and diversity of the microbial world was not fully understood until sequencing technology allowed us to study microbes without growing them in the lab. An important family of bacteria, Saccharibacteria (formerly called TM7), is one of the many bacteria of interest which were...
Scientific Pioneers
JCVI recognizes trailblazers in scientific history, particularly those who made advancements all while surpassing gender, ethnic, and other societal barriers, creating opportunity for the next generation of scientists. These historical figures not only helped advance our understanding of human...
Women’s History Month: Tu Youyou
Tu Youyou is a Chinese pharmaceutical chemist whose unique training in the classification of medical plants and their active ingredients resulted in a discovery that has led to the survival and improved health of millions of people. In 1967, at the height of the Vietnam War, malaria spread by...
SARS-CoV-2 Mutation Tracking
The Bacterial Viral Bioinformatic Resource Center (BV-BRC) is proud to introduce a new resource with the goal of providing live tracking of SARS-CoV-2 mutations. This real-time resource will provide regular reports focused on “Variants and Lineages of Concern” (VoCs/LoCs), and will serve as an early warning system for variants that are increasing in frequency in specific geographical locations.
JCVI Scientists and Interns Dramatically Trim Proteome Analysis Costs with New Lab-on-a-Filter Process
Through a happy accident and a keen mind, JCVI intern Rodrigo Eguez realized scientists might be able to pack their own filters rather than rely on those produced commercially at a significant cost savings. While playing around in the laboratory, he inadvertently disassembled a filter device...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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