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More Extensive Analysis Casts Doubt on Claim of Bacterial Genes in Humans
New findings do not support a recent analysis of the rough draft of the human genome that suggests that bacterial genes have been laterally transferred into the human genome.
TIGR Awarded Grant to Sequence Deadly Fungal Disease
The TIGR Comprehensive Microbial Resource (CMR) has been updated with six new genomes
Invitrogen Completes Worldwide Distribution Agreement with The Institute for Genomic Research
Invitrogen to Distribute TIGR's Gene Libraries
Qiagen Genomics Signs Tuberculosis SNP Genotyping Research and License Agreement with TIGR and Montefiore Medical Center
Groups collaborate to analyze genetic variation in different strains of M. tuberculosis
International Network for the Sequencing of Anopheles gambiae Genome
<em>Anopheles gambiae</em> Genome Sequencing Project
TIGR to Participate in Sequencing the Rat Genome
GeneSplicer is a fast, flexible software system for detecting splice sites in the genomic DNA of various eukaryotes.
TIGRFAMs are protein families based on Hidden Markov Models or HMMs.
2001 Summer Fellowship/Internship Information and Application now available (Deadline is Mar. 1)
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Scientist Spotlight: Hamilton O. Smith and Clyde A. Hutchison III
Editor’s note: Clyde Hutchison died on September 27, 2025. Less than a month later, Hamilton Smith died on October 25, 2025. This post memorializes their dear friendship and the quest to construct the first bacterium with a synthetic genome in 2010. Their friendship endured and their work...
Happy DNA Day!
This past March, we had a great time participating in the science programs in San Diego. We ended the month with the SD Science Festival with over 30,000 participants. It was such a busy day - I forgot to take pictures. The venue was Petco Park with hundreds of exhibits and hands-on experiences. We...
Recomb - Computational Proteomics
I recently attended the Recomb satellite conference on Computational Proteomics (downloads for talk and poster) in San Diego, CA. It was a kind of homecoming for me. I was a computational proteomics researcher at UCSD as a grad student with Vineet Bafna. Many of my classmates were still there, as...
A Positive Charge
I’m thinking of the day’s schedule school visit, the activity and the positive charge it will produce in me and the students. I get so excited during our school visits. It’s like the feeling I get on Saturday morning while watching my favorite cartoons. (Yes, I still watch...
We Had Fun with Genomics!
Wow! It’s been an exciting week!! Crystal Snowden and I flew to San Diego Friday, March 5th – jumped off the plane and the fun began! We went straight to the lab and set up for BEWiSE and prepped for Expanding Your Horizons (EYH). We are really fortunate to have such a great team in the San...
Scientist Spotlight: Orianna Bretschger
Most of us have never thought about how to make more water or cleaner water or develop unique sources of energy but that’s exactly what Orianna Bretschger does at JCVI. She is working at the intersection of engineering, physics, and biology to design small machines powered by bacteria that can...
Having Fun with Genomics
I am the generation after landing on the moon. As a child, I don’t recall having any science inspiration. I was fortunate to have parents that made it possible for me and my siblings to get a very good education. I went to a small parochial school outside of Washington, DC. It was a great school...
AGBT, Marco Island 2010
I just got back from AGBT in Marco Island, Florida and I am still in awe. As noted in the name, this conference highlights advances in both genome biology and technology. The biology seemed to be very human genome centric. Many of the talks presented full genome sequences of cancer genomes or...
Influenza H1N1pdm sequencing project overview
Since 2004, the JCVI Influenza Genome Sequencing Project, funded by the National Institute of Allergy and Infectious Diseases (NIAID), has sequenced thousands of human, swine, and avian influenza isolates from collections around the world to provide researchers with a better understanding of the...
High Impact Science in Antarctica
Big changes in store for the Mertz Polynya: in February 2010 iceberg 9B9 collided with the Mertz Glacier, breaking the 70 km floating glacier off at the base. The Mertz Polynya was extensivley sampled by scientists at the JCVI in the summer of 2007/08, and this metagenomic survey will form an important baseline for evaluating on-going changes in the area.
The race to stop mirror organisms
If created, these versions of the building blocks of life could lead to environmental and ecological disaster
J. Craig Venter Describes a Human Genomics Revolution Still In Progress
Despite profound impact on bio-medical research, progress in understanding has been slow
Scientist renowned for study of adolescent brains named president of J. Craig Venter Institute
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to JCVI.
Mirror Bacteria Research Poses Significant Risks, Dozens of Scientists Warn
Synthetic biologists make artificial cells, but one particular kind isn’t worth the risk.
Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
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