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Exploring Bacterial Branches of the Tree of Life
In an ambitious "phylogenomics" project, TIGR scientists have received an NSF grant to use whole genome sequence analysis to better understand the phylogenetic relationships among major bacterial groups.
Announcing the release of two packages useful in the analysis of shotgun sequence assembly data
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators.
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators. The list of 43 "emerging leaders who are reshaping our world" -- including nine scientists -- appears in the magazine's December issue.
TIGR Cracks Genome of Potential Bioremediation Agent
Scientists at TIGR and their collaborators have deciphered the genome sequence of the bacterium Shewanella oneidensis, which has great potential as a bioremediation agent to remove toxic metals such as chromium and uranium from the environment.
Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
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New Sequencing Technologies Enable Better and Faster Understanding of the Human Microbiome
Humans have trillions of different species of microorganisms living inside and on the human body. These microbes colonize on the skin, gut, oral cavity, vagina, internal organs, and circulating fluids, and are called the human microbiome. The human microbiome plays profound roles in health...
Human Microbiome Research has Massive Potential for Health Applications
Thirteen years ago, a team led by J. Craig Venter Institute President, Karen Nelson, Ph.D., published the first major human microbiome study, radically changing the way we look at human health and the role the microbes that inhabit each of us play in disease. This seminal publication...
Scientist Spotlight: Lauren Oldfield
Since high school, Lauren Oldfield, PhD found that science was her calling. It started with a love of reading encouraged by her mom and grandmother, both avid readers, and weekly trips to the public library. Books by Michael Crichton and Richard Preston were staples in her grandmother’s...
When Starved, Dangerous Oral Bacteria Hang On
J. Craig Venter Institute (JCVI) postdoctoral fellow, Jonathon Baker, PhD and a team of researchers from JCVI, University of Washington, the University of California, Los Angeles, and The Forsyth Institute recently published their findings from the first study to examine the ecological dynamics...
No More Needles! Using Microbiome and Synthetic Biology Advances to Better Treat Type 1 Diabetes
Learn about exciting advances made by JCVI researchers Yo Suzuki and John Glass who are on a quest to better understand and treat Type 1 Diabetes (T1D). Currently T1D is managed by injecting insulin to manage blood glucose levels. Drs. Suzuki and Glass want to change that by creating a...
How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at JCVI Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae...
Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
Scientist Spotlight: Marcelo Freire
Marcelo Freire, an associate professor in the Genomic Medicine and Infectious Disease Department at the J. Craig Venter Institute (JCVI), is currently working on decoding immune-microbiome genes and interactions. Growing up in Brazil and a curious person by nature, he often found himself...
Tracking Enterovirus D68, Cause of a Polio-like Illness in Some Patients
The J. Craig Venter Institute (JCVI) has played a vital role in defining the diversity of contemporary strains of human enteroviruses by using state-of-the art sequencing technologies, bioinformatics analyses, and in vitro and in vivo modeling.
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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