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Scientists find evidence that novel coronavirus infects the mouth’s cells
NIH-funded findings point to a role for saliva in SARS-CoV-2 transmission.
Scientists map how iron, a critical mineral for survival, is processed by algae, a cornerstone of the ocean food web
Nearly forty proteins identified in the intracellular process, helping to build a conceptual overview of how iron is allocated within diatom cells
J. Craig Venter Institute Scientists to Investigate Role of Opioid Abuse in HIV and HIV-Associated Neurocognitive Disorders Pathogenesis through $4.7M NIDA Grant
Study aims to identify candidate molecules to regulate HIV infection in the central nervous system in patients abusing opioids
Influenza A Virus Discovered in Heart Muscle Tissue Causing Damage Long After It Has Cleared from the Lungs
Strategies to inhibit necrotic cell death or to prevent mitochondrial damage should be pursued as possible therapies to reduce cardiac damage during influenza infections
Hamilton O. Smith, M.D., Synthetic Biology Pioneer and Nobel Laureate, to Step Down from Daily Duties at J. Craig Venter Institute
Dr. Smith will maintain advisory role as professor emeritus
Scientists set a path for field trials of gene drive organisms
As genetically engineered organisms ramp up, a multidisciplinary coalition offers a framework for ethical, socially engaged and transparent field practices
JCVI President Karen Nelson, Ph.D., Recognized as Global Scientific Pioneer on Clarivate’s Highly Cited Researcher 2020 List
Study reveals mouth as primary source of COVID-19 infection, spread
UNC-Chapel Hill, NIH identify sites in the oral cavity where coronavirus can take hold
Dr. J. Craig Venter Awarded the 2020 Edogawa NICHE Prize
Biology in Art: Genetic Detectives ID Microbes Suspected of Slowly Ruining Humanity’s Treasures
DNA science may help restore, preserve historic works, unmask counterfeits
The trait elite baseball hitters share with Leonardo da Vinci: A “quick eye” with higher “frames per second.” A function of training, genetics, or both?
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JCVI Scientists and Interns Dramatically Trim Proteome Analysis Costs with New Lab-on-a-Filter Process
Through a happy accident and a keen mind, JCVI intern Rodrigo Eguez realized scientists might be able to pack their own filters rather than rely on those produced commercially at a significant cost savings. While playing around in the laboratory, he inadvertently disassembled a filter device...
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
While news of promising COVID-19 vaccine trials is heartening, the fight to control infection rates and develop effective treatments will be an ongoing challenge for science for years to come. Gene Tan, PhD and his collaborators are working on identifying...
Synthetic Cell-Powered Lotion to Manage Type 1 Diabetes
Early last year we first talked about how researchers Yo Suzuki, PhD, and John Glass, PhD at JCVI set out to eliminate the need for type 1 diabetes (T1D) patients to receive insulin injections to manage blood glucose levels through a novel approach: developing a bacterial replacement for beta...
COVID-19 Further Complicating Flu Season
While the world is rightly focused on the ongoing COVID-19 pandemic, it’s important to know that influenza is always a significant public health burden, and the combination of the pandemic and flu season could converge to become a perfect storm of infectious diseases. Influenza causes 3 to...
Sara Josephine Baker
At the beginning of the 20th century, many people remained skeptical of both germ theory and preventative medicine, but pioneering physician Dr. Sara Josephine Baker fought to revolutionize public health and is credited with saving tens of thousands of lives. After studying chemistry and...
JCVI Researchers Help Advance Our Understanding of Ocean Microbes, Developing New Tools and Protocols Through Large-Scale Study
The oceans cover over two-thirds of the Earth’s surface and contain an abundance of life including diverse populations of marine microbes. Studying the genetics, biochemistry and metabolism of these microbes has been one of JCVI’s long standing research initiatives and is...
Online Education Resources to Help With Your New “Normal”
The COVID-19 pandemic has brought many changes to our daily lives and routines, including for many of you the role of an at-home educator for your children due to open-ended school closures. While we also miss directly connecting with students from our community, JCVI remains committed...
Coronavirus Pandemic: Putting Comprehensive Genomic Data in the Hands of Frontline Researchers Worldwide is Paramount
According to the CDC, SARS-CoV-2, the virus causing COVID-19, has now been detected in more than 150 countries/locations internationally. The World Health Organization (WHO) has declared COVID-19 a pandemic, and in the United States it has been declared it a national emergency. As...
Characterization of Bacteria from the International Space Station Drinking Water
From a microbiology perspective, the International Space Station (ISS) is interesting considering its microgravity, increased radiation, low humidity and elevated carbon dioxide levels. Because of its isolation, and unique environment, it is vital to study the microorganisms that thrive there...
Venter Institute Researchers Tackle the Growing Concern of Antibiotic Resistant Bacterial Infections with Genomic, Phage Approaches
The Centers for Disease Control and Prevention (CDC) estimates that each year in the United States two million people acquire antibiotic resistant bacterial infections that lead to 23,000 deaths. Antibiotic resistance affects people of all ages and seriously impacts the healthcare, veterinary,...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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