Viral

Keeping up with 21st century viruses has proven to be a tall task. Leveraging genomics, bioinformatics and synthetic genomics expertise at JCVI, coupled with conventional scientific approaches, we are committed to developing better vaccines and therapeutics, by gaining a deeper understanding of how viruses cause disease.

Investigating Viral Disease to Develop Next Generation Vaccines and Therapeutics

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Vaccines and Therapeutics for Zika

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Antigenic Map of Lyssavirus (Rabies Virus)

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Virus Evolution and Protective Immunity to Influenza

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Influenza: Host-Virus-Microbiome Interactions

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Genetic Diversity and Evolutionary Dynamics of Respiratory Syncytial Viruses (RSV)

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Genetic Diversity and Evolutionary Dynamics of Influenza A and B Viruses

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Genomics of Chikungunya Virus

Sequencing Chikungunya virus genomes isolated from the Western hemisphere during the 2014 Caribbean outbreak

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Genomics of Zika Virus

Investigating the genomics of Zika virus throughout the Americas

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Genomics of Rotavirus

Sequencing Rotavirus genomes isolated from around the world

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Genomics of West Nile Virus

Sequencing West Nile virus genomes isolated in the United States

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Genomics of Respiratory Syncytial Virus

Sequencing clinical isolates of Respiratory Syncytial Virus in various locations

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Genomics of Influenza A and Influenza B Viruses

Sequencing Influenza genomes isolated from various hosts and locations

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A Bioinformatics Roadmap for the Human Vaccines Project

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Age-Associated Determinants of Alveolar Macrophage-Mediated Antiviral and Inflammatory Responses

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Engineering a Self-Amplifying RNA Amplicon as a Vaccine or Therapeutic for Influenza

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Hepatitis B Vaccine Response

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Virus Pathogen Resource (ViPR)

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Influenza Research Database (IRD)

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Developing Genetic Tools to Manipulate African Swine Fever Virus and Generate Attenuated Strains

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Chronic Wound Microbiome

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Development of Serodiagnostics for Mosquito-Borne Virus

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Herpesvirus Ortholog Prediction

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EV-D68 Replication in Human Neuronal Cells

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BREAD: Toward Development of a Vaccine for Contagious Bovine Pleuropneumonia (CBPP)

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Genetic Diversity and Evolutionary Dynamics of West Nile Viruses

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Genetic Diversity and Evolutionary Dynamics of Eastern Equine Encephalitis Viruses (EEEV)

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Genetic Diversity and Evolutionary Dynamics of Rotaviruses

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Respiratory Syncytial Virus: Host-Virus-Microbiome Interactions

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Impact of Viral Intra-Host Diversity on Transmission Dynamics and Antiviral Resistance

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Genomics of Filoviruses

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Synthetic Genomics to Generate a Stable Epstein-Barr Virus Infectious Clone

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Genomics of Eastern Equine Encephalitis Virus

Elucidating transmission of EEEV in the United States

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Genomics of Marburg and Ebola Viruses

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Global H1 Influenza Nomenclature

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Viral Synthetic Genomics to Engineer Large dsDNA Viruses

Rapid engineering of large dsDNA viruses using synthetic genomics assembly tools.

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Assembly of HSV-1

Use of cutting-edge synthetic genomics technology to revolutionize the study of herpesvirus biology.

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Mature Zika Peptides

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A Synthetic Human Cytomegalovirus Vaccine Platform

Generation of an HCMV low passage clinical isolate using synthetic genomics.

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26-May-2020
Press Release

Maintaining a Healthy Upper Respiratory Tract Microbiome May Help Prevent Secondary Infections in Influenza A Patients

An influenza-impacted upper respiratory tract microbiome may invite opportunistic bacterial pathogens

05-Nov-2018
Blog

Fighting Back Against Flu

20-Feb-2018
Collaborator Release

Past encounters with the flu shape vaccine response

Immune history influences vaccine effectiveness, interacting with other potential problems arising from the manufacturing process

Development of a Multivalent Rhinovirus Vaccine

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Rotavirus Genomics and Metagenomics of African Stool Samples

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Arbovirus Sequencing Project II

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Role of the Untranslated Regions of the Influenza a Virus Replication and Vaccines

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Transmission Kinetics of RSV Infection

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