Viral
Overview
Keeping up with 21st century viruses has proven to be a tall task. Leveraging genomics, bioinformatics and synthetic genomics expertise at JCVI, coupled with conventional scientific approaches, we are committed to developing better vaccines and therapeutics, by gaining a deeper understanding of how viruses cause disease.
Coronavirus Research
Projects
Coronavirus Research
Overview of various projects related to the novel coronavirus pandemic.Mechanisms of Influenza Driven Cardiac Dysfunction
This research will give us a better understanding of the full spectrum of the pathogenesis of influenza and other viruses like it.Genomics of Chikungunya Virus
Sequencing Chikungunya virus genomes isolated from the Western hemisphere during the 2014 Caribbean outbreak
Genomics of Zika Virus
Investigating the genomics of Zika virus throughout the Americas
Genomics of Rotavirus
Sequencing Rotavirus genomes isolated from around the world
Genomics of West Nile Virus
Sequencing West Nile virus genomes isolated in the United States
Genomics of Respiratory Syncytial Virus
Sequencing clinical isolates of Respiratory Syncytial Virus in various locations
Genomics of Influenza A and Influenza B Viruses
Sequencing Influenza genomes isolated from various hosts and locations
Genomics of Eastern Equine Encephalitis Virus
Elucidating transmission of EEEV in the United States
Viral Synthetic Genomics to Engineer Large dsDNA Viruses
Rapid engineering of large dsDNA viruses using synthetic genomics assembly tools.
Assembly of HSV-1
Use of cutting-edge synthetic genomics technology to revolutionize the study of herpesvirus biology.
A Synthetic Human Cytomegalovirus Vaccine Platform
Generation of an HCMV low passage clinical isolate using synthetic genomics.
Team
News
Researchers design tools to develop vaccines more efficiently for African swine fever virus (ASFV)
The reverse-genetics system developed for ASFV may be adapted for other viruses, including lumpy skin disease, Zika, chikungunya, and Ebola viruses
Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
New LongCOVID research launched by PolyBio’s global consortium of scientists
Funding will deepen research on the persistence of the SARS-CoV-2 virus in LongCOVID patients and launch new clinical trials
J. Craig Venter Institute scientists awarded five-year, $5.7M grant from NIH to develop phage treatment
Phage research accelerates with the rise of antibiotic resistance to address increasingly prevalent and difficult to treat bacterial infections
PolyBio Research Foundation Consortium & colleagues publishes Nature position paper on SARS-CoV-2 reservoir in Long COVID/PASC
Using AI to speed up vaccine development against Disease X
Family resemblance: How T cells could fight many coronaviruses at once
LJI researchers work to head off future pandemics by uncovering key similarities between SARS-CoV-2 and common cold coronaviruses
Scientists aim to develop vaccine against all deadly coronaviruses
$8 million NIH grant supports effort to avert next pandemic
Top scientists join forces to study leading theory behind long COVID
Several JCVI scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Omicron and Beta variants evade antibodies elicited by vaccines and previous infections, but boosters help
Pregnancy also contributes to a reduced COVID-19 antibody response
SARS-CoV-2 Mutation Tracking
J. Craig Venter Institute Scientists to Investigate Role of Opioid Abuse in HIV and HIV-Associated Neurocognitive Disorders Pathogenesis through $4.7M NIDA Grant
Study aims to identify candidate molecules to regulate HIV infection in the central nervous system in patients abusing opioids
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
Maintaining a Healthy Upper Respiratory Tract Microbiome May Help Prevent Secondary Infections in Influenza A Patients
An influenza-impacted upper respiratory tract microbiome may invite opportunistic bacterial pathogens
Fighting Back Against Flu
Every Day is World Food Day at JCVI
Past encounters with the flu shape vaccine response
Immune history influences vaccine effectiveness, interacting with other potential problems arising from the manufacturing process