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Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
TIGR investigators announced today that they have determined the complete genome sequence of a green-sulfur bacterium, Chlorobium tepidum
TIGR's new publication, the TIGR Triptych, features articles about Bacillus anthracis research and the new Pathogen Functional Genomics Resource Center
An Arabidopsis whole genome chip jointly developed by TIGR and Affymetrix Inc. has been completed and is now being tested
Scientists Find New Markers For Anthrax Isolates
In a pioneering use of genomics as a tool for the forensic analysis of microbes, TIGR scientists have found new genetic markers to distinguish the Bacillus anthracis isolate that was used in last fall's bioterror attack in Florida from closely related anthrax strains.
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Sea-ice class
Today Abigail Noble and I took a Hagglund transporter out onto the Ross Sea to learn the basics of sea ice safety and ice dynamics. The sea ice on McMurdo Sound can be 2 meters thick, but this ice is constantly changing, and when you drive along its surface, you can't assume that it is uniformly 2...
Happy Camp
Our project on the Ross Sea will take us far from heated facilities of McMurdo Station, so all members of our team need to attend "Happy Camp", a two day course on snow camping and basic Antarctic survival. Happy Camp is held out on the McMurdo Ice Shelf, and it is an immersion program in the true...
McMurdo Station
Entering McMurdo is like entering a modern mining town: lots of exposed rock and unpaved streets, above ground utilities and bare-bones architecture. Utilitarian. From the airport we were taken to a briefing room, introduced to our science coordinators, and given our shcedules. Since I am new to...
Transport to the ice
Wednesday morning started with a 5AM taxi ride to the US Antarctic Program's processing center at the Christchurch airport, where we had to repack our bags and put on our emergency cold weather gear for the flight. Our plane was the C-17 Globemaster III, a large military transport plane more...
Polynya opens in the Ross Sea
A helicopter pilot recently sent us an image of the area we are planning to sample, and the stable sea ice we intended to use as a platform for drilling and sampling is now a giant stretch of open seawater! A large opening like this is a polynya, a term borrowed from the Russian meaning...
Christchurch, New Zealand
Greetings from Christchurch, New Zealand, the anteroom to Antarctica. My colleagues and I have been here for several days now, running last minute errands, getting equipped with cold weather gear, and waiting for a flight south to McMurdo Station. The flight here was remarkable only in it's length:...
Why Antarctica, and why now?
So why are you going to Antarctica, and why are you going now? A very logical question... basically we are traveling to Antarctica to study microscopic marine plants known as phytoplankton. These organisms range in size from bacteria to diatoms to colonial algae, but all phytoplankton have two...
Trip preparations (inaugural posting!)
Well, we have less than a week left, and we are finalizing and shipping the chemicals and equipment we will need for sampling below the sea ice in the Ross Sea. We have already shipped out several hundred pounds of gear, and more await us in storage down at McMurdo Station in Antarctica. Expedition...
Going west!
After saying good bye to our new friends in Rostock/Warnemünde I was looking forward to coming back to Swedish waters, this time a bit saltier, on the west coast. There are two marine field stations on the Swedish west coast belonging to The Sven Lovén Center for Marine Sciences. Our first stop...
In the bloom...almost
Cyanobacterial blooms during the summer are reoccurring phenomena in the Baltic Sea. This summer we have already encountered the two main species responsible the blooms, Aphanizomenon sp. and the toxin producing Nodularia spumigena (see previous posts), but so far not in the abundance that would...
Reflections on the 20th Anniversary of the First Publication of the Human Genome
A new wave of research is needed to make ample use of humanity’s “most wondrous map”
Scientists rush to determine if mutant strain of coronavirus will deepen pandemic
U.S. researchers have been slow to perform the genetic sequencing that will help clarify the situation
After saving countless lives, Nobel laureate Hamilton Smith retires as his own health falters
He has been a fixture in San Diego science for decades
The 'Wondrous Map': Charting of the Human Genome, 20 Years Later
Twenty years ago, President Bill Clinton announced completion of what was arguably one of the greatest advances of the modern era: the first draft sequence of the human genome.
Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
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