Bio

Andrew E. Allen is a professor in the Microbial and Environmental Genomics Department. His research focus is related to genome biology, and comparative and functional genomics of eukaryotic marine phytoplankton. Other areas of interest include molecular microbial ecology and metagenomics of eukaryotic marine microbes and bacteria, molecular and genome evolution, chemical and biological oceanography, microbial metabolism, and bioinformatics. Primary areas of interest are based on understanding the molecular basis of carbon (C), nitrogen (N), and iron (Fe) assimilation and metabolism in marine phytoplankton populations as well as the evolution and ecological relevance of molecular and regulatory and signaling/sensing mechanisms that mediate acclimation responses to nutrient and abiotic stress and control biotic interactions. Various ongoing physiological and functional genomics based wet-lab, computational, metagenomic, and metatranscriptomic research projects are centered on addressing hypotheses related to controls on the diversity and activity of marine microorganisms.

Prior to joining JCVI, Dr. Allen was a postdoctoral fellow at the École Normale Supérieure in Paris, France and at Princeton University in the labs of Chris Bowler and Bess Ward where he worked on phytoplankton genomics. He received his PhD in Ecology from the University of Georgia under the direction of Marc Frischer and Peter Verity where he studied the molecular basis of nitrogen assimilation in marine bacteria. Dr. Allen earned his bachelor's degree in Biology and English from Vassar College.

Publications

Publications

Harmful algae. 2026-01-01; 151.103024.

A digital PCR assay for the dabA gene involved in domoic acid biosynthesis by Pseudo-nitzschia spp

Weinstock C, Preston C, Brunson JK, Ussler W, Bowers H, Yamahara K, Doucette G, Ryan J, Allen A, Scholin C, Birch J
PMID: 41350003

mBio. 2025-12-10; 16.12: e0207925.

Domoic acid biosynthesis and genome expansion in Nitzschia navis-varingica

Wood-Rocca SM, Allsing N, Ashida Y, Mochizuki M, Moore ML, Füssy Z, Kotaki Y, Puilingi C, Maeno Y, Beattie AW, Allen AE, Yotsu-Yamashita M, Michael TP, Moore BS
PMID: 41165336

Journal of phycology. 2025-12-01; 61.6: 1591-1600.

An undescribed species within the Gymnodinium sensu stricto group found responsible for an exceptional bloom in the Southern Ocean

Mascioni M, Cusick A, Sanchez-Puerta MV, Johnson C, Zheng H, Reynolds RA, Allen AE, Almandoz GO
PMID: 41014142

Nature communications. 2025-09-29; 16.1: 8559.

Genome-resolved biogeography of Phaeocystales, cosmopolitan bloom-forming algae

Füssy Z, Lampe RH, Arrigo KR, Barry K, Brisbin MM, Brussaard CPD, Decelle J, de Vargas C, Ditullio GR, Elbourne LDH, Frischer ME, Goodstein DM, Grigoriev IV, Hayes RD, Healey AL, James CC, Jenkins JW, Juery C, Kumar M, Kustka AB, Maumus F, Novák Vanclová AMG, Oborník M, Paulsen IT, Probert I, Saito MA, Schmutz J, Skalický T, Tec-Campos D, Tomelka H, Věchtová P, Venepally P, Wilson-Mortier B, Zengler K, Zheng H, Allen AE
PMID: 41022706

Microbiology resource announcements. 2025-07-10; 14.7: e0029825.

Marine microbial mock communities for validating rRNA gene amplicon sequencing

Lampe RH, Rabines AJ, Ellman BA, Zheng H, Allen AE
PMID: 40444952

Science (New York, N.Y.). 2025-07-10; 389.6756: 176-182.

Overturning circulation structures the microbial functional seascape of the South Pacific

Kolody BC, Sachdeva R, Zheng H, Füssy Z, Tsang E, Sonnerup RE, Purkey SG, Allen EE, Banfield JF, Allen AE
PMID: 40638745

Current biology : CB. 2025-05-19; 35.10: 2240-2255.e6.

Cathepsin X is a conserved cell death protein involved in algal response to environmental stress

Mizrachi A, Sadeh M, Ben-Dor S, Dym O, Ku C, Feldmesser E, Zarfin A, Brunson JK, Allen AE, Jinkerson RE, Schatz D, Vardi A
PMID: 40233752

Annual review of microbiology. 2024-11-07; 78.1: 213-232.

Molecular Mechanisms for Iron Uptake and Homeostasis in Marine Eukaryotic Phytoplankton

Lampe RH, Coale TH, McQuaid JB, Allen AE
PMID: 39018471

Proceedings of the National Academy of Sciences of the United States of America. 2024-10-01; 121.40: e2319177121.

Molecular forecasting of domoic acid during a pervasive toxic diatom bloom

Brunson JK, Thukral M, Ryan JP, Anderson CR, Kolody BC, James CC, Chavez FP, Leaw CP, Rabines AJ, Venepally P, Fussy Z, Zheng H, Kudela RM, Smith GJ, Moore BS, Allen AE
PMID: 39298472

Scientific reports. 2024-09-28; 14.1: 22408.

Endemic, cosmopolitan, and generalist taxa and their habitat affinities within a coastal marine microbiome

James CC, Allen AE, Lampe RH, Rabines A, Barton AD
PMID: 39333653

Applied and environmental microbiology. 2024-08-21; 90.8: e0108324.

Metatranscriptomic response of deep ocean microbial populations to infusions of oil and/or synthetic chemical dispersant

Peña-Montenegro TD, Kleindienst S, Allen AE, Eren AM, McCrow JP, Arnold J, Joye SB
PMID: 39041797

Plant physiology. 2024-05-26;

Delta-5 elongase knockout reduces docosahexaenoic acid and lipid synthesis and increases heat sensitivity in a diatom

Zhu J, Li S, Chen W, Xu X, Wang X, Wang X, Han J, Jouhet J, Amato A, Maréchal E, Hu H, Allen AE, Gong Y, Jiang H
PMID: 38796833

Proceedings of the National Academy of Sciences of the United States of America. 2024-02-06; 121.6: e2204075121.

Flexible B12 ecophysiology of Phaeocystis antarctica due to a fusion B12-independent methionine synthase with widespread homologues

Rao D, Füssy Z, Brisbin MM, McIlvin MR, Moran DM, Allen AE, Follows MJ, Saito MA
PMID: 38306482

The New phytologist. 2024-02-01; 241.4: 1543-1558.

Two plastidial lysophosphatidic acid acyltransferases differentially mediate the biosynthesis of membrane lipids and triacylglycerols in Phaeodactylum tricornutum

You L, Połońska A, Jasieniecka-Gazarkiewicz K, Richard F, Jouhet J, Maréchal E, Banaś A, Hu H, Pan Y, Hao X, Jin H, Allen AE, Amato A, Gong Y
PMID: 38031462

The ISME journal. 2024-01-08; 18.1:

Iron limitation of heterotrophic bacteria in the California Current System tracks relative availability of organic carbon and iron

Manck LE, Coale TH, Stephens BM, Forsch KO, Aluwihare LI, Dupont CL, Allen AE, Barbeau KA
PMID: 38624181

The ISME journal. 2024-01-08; 18.1:

Transportome remodeling of a symbiotic microalga inside a planktonic host

Juéry C, Auladell A, Füssy Z, Chevalier F, Yee DP, Pelletier E, Corre E, Allen AE, Richter DJ, Decelle J
PMID: 39658219

The ISME journal. 2023-12-01; 17.12: 2147-2159.

Progress and challenges in exploring aquatic microbial communities using non-targeted metabolomics

Thukral M, Allen AE, Petras D
PMID: 37857709

The ISME journal. 2023-12-01; 17.12: 2459.

Publisher Correction: Progress and challenges in exploring aquatic microbial communities using non-targeted metabolomics

Thukral M, Allen AE, Petras D
PMID: 37993599

Nature communications. 2023-11-08; 14.1: 7215.

Short-term acidification promotes diverse iron acquisition and conservation mechanisms in upwelling-associated phytoplankton

Lampe RH, Coale TH, Forsch KO, Jabre LJ, Kekuewa S, Bertrand EM, Horák A, Oborník M, Rabines AJ, Rowland E, Zheng H, Andersson AJ, Barbeau KA, Allen AE
PMID: 37940668

ISME communications. 2023-09-22; 3.1: 99.

Species-specific responses of marine bacteria to environmental perturbation

Peña-Montenegro TD, Kleindienst S, Allen AE, Eren AM, McCrow JP, Sánchez-Calderón JD, Arnold J, Joye SB
PMID: 37736763

Applied and environmental microbiology. 2023-07-26; 89.7: e0031823.

Host and Water Microbiota Are Differentially Linked to Potential Human Pathogen Accumulation in Oysters

Diner RE, Zimmer-Faust A, Cooksey E, Allard S, Kodera SM, Kunselman E, Garodia Y, Verhougstraete MP, Allen AE, Griffith J, Gilbert JA
PMID: 37318344

Plant direct. 2022-12-26; 6.12: e472.

In vivo localization of iron starvation induced proteins under variable iron supplementation regimes in Phaeodactylum tricornutum

Kazamia E, Mach J, McQuaid JB, Gao X, Coale TH, Malych R, Camadro JM, Lesuisse E, Allen AE, Bowler C, Sutak R
PMID: 36582220

Environmental microbiology. 2022-11-01; 24.11: 5408-5424.

Illuminating the dark metabolome of Pseudo-nitzschia-microbiome associations

Koester I, Quinlan ZA, Nothias LF, White ME, Rabines A, Petras D, Brunson JK, Dührkop K, Ludwig M, Böcker S, Azam F, Allen AE, Dorrestein PC, Aluwihare LI
PMID: 36222155

Nature communications. 2022-05-18; 13.1: 2887.

Publisher Correction: Influence of nutrient supply on plankton microbiome biodiversity and distribution in a coastal upwelling region

James CC, Barton AD, Allen LZ, Lampe RH, Rabines A, Schulberg A, Zheng H, Goericke R, Goodwin KD, Allen AE
PMID: 35585093

Nature communications. 2022-05-04; 13.1: 2448.

Influence of nutrient supply on plankton microbiome biodiversity and distribution in a coastal upwelling region

James CC, Barton AD, Allen LZ, Lampe RH, Rabines A, Schulberg A, Zheng H, Goericke R, Goodwin KD, Allen AE
PMID: 35508497

Nature communications. 2022-04-14; 13.1: 1995.

Adaptive responses of marine diatoms to zinc scarcity and ecological implications

Kellogg RM, Moosburner MA, Cohen NR, Hawco NJ, McIlvin MR, Moran DM, Ditullio GR, Subhas AV, Allen AE, Saito MA
PMID: 35422102

Proceedings of the National Academy of Sciences of the United States of America. 2022-02-08; 119.6:

Domoic acid biosynthesis in the red alga Chondria armata suggests a complex evolutionary history for toxin production

Steele TS, Brunson JK, Maeno Y, Terada R, Allen AE, Yotsu-Yamashita M, Chekan JR, Moore BS
PMID: 35110408

Journal of phycology. 2022-02-01; 58.1: 36-54.

Blowin' in the wind: Dispersal, structure, and metacommunity dynamics of aeolian diatoms in the McMurdo Sound region, Antarctica

Schulte NO, Khan AL, Smith EW, Zoumplis A, Kaul D, Allen AE, Adams BJ, McKnight DM
PMID: 34817069

Nature methods. 2022-02-01; 19.2: 134-136.

GNPS Dashboard: collaborative exploration of mass spectrometry data in the web browser

Petras D, Phelan VV, Acharya D, Allen AE, Aron AT, Bandeira N, Bowen BP, Belle-Oudry D, Boecker S, Cummings DA, Deutsch JM, Fahy E, Garg N, Gregor R, Handelsman J, Navarro-Hoyos M, Jarmusch AK, Jarmusch SA, Louie K, Maloney KN, Marty MT, Meijler MM, Mizrahi I, Neve RL, Northen TR, Molina-Santiago C, Panitchpakdi M, Pullman B, Puri AW, Schmid R, Subramaniam S, Thukral M, Vasquez-Castro F, Dorrestein PC, Wang M
PMID: 34862502

The New phytologist. 2022-02-01; 233.4: 1797-1812.

Multiplexed CRISPR/Cas9 editing of the long-chain acyl-CoA synthetase family in the diatom Phaeodactylum tricornutum reveals that mitochondrial ptACSL3 is involved in the synthesis of storage lipids

Hao X, Chen W, Amato A, Jouhet J, Maréchal E, Moog D, Hu H, Jin H, You L, Huang F, Moosburner M, Allen AE, Gong Y
PMID: 34882804

The ISME journal. 2022-02-01; 16.2: 569-579.

Proteomic traits vary across taxa in a coastal Antarctic phytoplankton bloom

McCain JSP, Allen AE, Bertrand EM
PMID: 34482372

Plant direct. 2022-01-20; 6.1: e376.

Proteomic analysis of metabolic pathways supports chloroplast-mitochondria cross-talk in a Cu-limited diatom

Hippmann AA, Schuback N, Moon KM, McCrow JP, Allen AE, Foster LF, Green BR, Maldonado MT
PMID: 35079683

Environmental microbiology. 2021-11-01; 23.11: 6734-6748.

Relating sinking and suspended microbial communities in the California Current Ecosystem: digestion resistance and the contributions of phytoplankton taxa to export

Valencia B, Stukel MR, Allen AE, McCrow JP, Rabines A, Palenik B, Landry MR
PMID: 34431195

mSystems. 2021-08-31; 6.4: e0057121.

Pathogenic Vibrio Species Are Associated with Distinct Environmental Niches and Planktonic Taxa in Southern California (USA) Aquatic Microbiomes

Diner RE, Kaul D, Rabines A, Zheng H, Steele JA, Griffith JF, Allen AE
PMID: 34227831

Science advances. 2021-08-06; 7.32:

Cellular costs underpin micronutrient limitation in phytoplankton

McCain JSP, Tagliabue A, Susko E, Achterberg EP, Allen AE, Bertrand EM
PMID: 34362734

Scientific reports. 2021-08-02; 11.1: 15592.

Diploid genomic architecture of Nitzschia inconspicua, an elite biomass production diatom

Oliver A, Podell S, Pinowska A, Traller JC, Smith SR, McClure R, Beliaev A, Bohutskyi P, Hill EA, Rabines A, Zheng H, Allen LZ, Kuo A, Grigoriev IV, Allen AE, Hazlebeck D, Allen EE
PMID: 34341414

Proceedings of the National Academy of Sciences of the United States of America. 2021-07-27; 118.30:

Molecular underpinnings and biogeochemical consequences of enhanced diatom growth in a warming Southern Ocean

Jabre LJ, Allen AE, McCain JSP, McCrow JP, Tenenbaum N, Spackeen JL, Sipler RE, Green BR, Bronk DA, Hutchins DA, Bertrand EM
PMID: 34301906

eLife. 2021-02-16; 10.

Proximity proteomics in a marine diatom reveals a putative cell surface-to-chloroplast iron trafficking pathway

Turnšek J, Brunson JK, Viedma MDPM, Deerinck TJ, Horák A, Oborník M, Bielinski VA, Allen AE
PMID: 33591270

Nature microbiology. 2021-02-01; 6.2: 173-186.

Dinoflagellates alter their carbon and nutrient metabolic strategies across environmental gradients in the central Pacific Ocean

Cohen NR, McIlvin MR, Moran DM, Held NA, Saunders JK, Hawco NJ, Brosnahan M, Ditullio GR, Lamborg C, McCrow JP, Dupont CL, Allen AE, Saito MA
PMID: 33398100

Science robotics. 2020-11-25; 5.48:

Revealing ocean-scale biochemical structure with a deep-diving vertical profiling autonomous vehicle

Breier JA, Jakuba MV, Saito MA, Dick GJ, Grim SL, Chan EW, McIlvin MR, Moran DM, Alanis BA, Allen AE, Dupont CL, Johnson R
PMID: 33239321

The New phytologist. 2020-11-01; 228.3: 946-958.

Mitochondrial fatty acid β-oxidation is required for storage-lipid catabolism in a marine diatom

Jallet D, Xing D, Hughes A, Moosburner M, Simmons MP, Allen AE, Peers G
PMID: 32535932

Scientific reports. 2020-10-07; 10.1: 16687.

Common origin of ornithine-urea cycle in opisthokonts and stramenopiles

Horák A, Allen AE, Oborník M
PMID: 33028894

Biology. 2020-07-06; 9.7:

The Importance of Protein Phosphorylation for Signaling and Metabolism in Response to Diel Light Cycling and Nutrient Availability in a Marine Diatom

Tan MH, Smith SR, Hixson KK, Tan J, McCarthy JK, Kustka AB, Allen AE
PMID: 32640597

Molecular ecology. 2020-06-24; 29.11: 2080-2093.

Sierra Nevada mountain lake microbial communities are structured by temperature, resources and geographic location

Schulhof MA, Allen AE, Allen EE, Mladenov N, McCrow JP, Jones NT, Blanton J, Cavalheri HB, Kaul D, Symons CC, Shurin JB
PMID: 32578266

Nature methods. 2020-05-01; 17.5: 481-494.

Genetic tool development in marine protists: emerging model organisms for experimental cell biology

Faktorová D, Nisbet RER, Fernández Robledo JA, Casacuberta E, Sudek L, Allen AE, Ares M, Aresté C, Balestreri C, Barbrook AC, Beardslee P, Bender S, Booth DS, Bouget FY, Bowler C, Breglia SA, Brownlee C, Burger G, Cerutti H, Cesaroni R, Chiurillo MA, Clemente T, Coles DB, Collier JL, Cooney EC, Coyne K, Docampo R, Dupont CL, Edgcomb V, Einarsson E, Elustondo PA, Federici F, Freire-Beneitez V, Freyria NJ, Fukuda K, García PA, Girguis PR, Gomaa F, Gornik SG, Guo J, Hampl V, Hanawa Y, Haro-Contreras ER, Hehenberger E, Highfield A, Hirakawa Y, Hopes A, Howe CJ, Hu I, Ibañez J, Irwin NAT, Ishii Y, Janowicz NE, Jones AC, Kachale A, Fujimura-Kamada K, Kaur B, Kaye JZ, Kazana E, Keeling PJ, King N, Klobutcher LA, Lander N, Lassadi I, Li Z, Lin S, Lozano JC, Luan F, Maruyama S, Matute T, Miceli C, Minagawa J, Moosburner M, Najle SR, Nanjappa D, Nimmo IC, Noble L, Novák Vanclová AMG, Nowacki M, Nuñez I, Pain A, Piersanti A, Pucciarelli S, Pyrih J, Rest JS, Rius M, Robertson D, Ruaud A, Ruiz-Trillo I, Sigg MA, Silver PA, Slamovits CH, Jason Smith G, Sprecher BN, Stern R, Swart EC, Tsaousis AD, Tsypin L, Turkewitz A, Turnšek J, Valach M, Vergé V, von Dassow P, von der Haar T, Waller RF, Wang L, Wen X, Wheeler G, Woods A, Zhang H, Mock T, Worden AZ, Lukeš J
PMID: 32251396

Nature methods. 2020-05-01; 17.5: 551.

Publisher Correction: Genetic tool development in marine protists: emerging model organisms for experimental cell biology

Faktorová D, Nisbet RER, Fernández Robledo JA, Casacuberta E, Sudek L, Allen AE, Ares M, Aresté C, Balestreri C, Barbrook AC, Beardslee P, Bender S, Booth DS, Bouget FY, Bowler C, Breglia SA, Brownlee C, Burger G, Cerutti H, Cesaroni R, Chiurillo MA, Clemente T, Coles DB, Collier JL, Cooney EC, Coyne K, Docampo R, Dupont CL, Edgcomb V, Einarsson E, Elustondo PA, Federici F, Freire-Beneitez V, Freyria NJ, Fukuda K, García PA, Girguis PR, Gomaa F, Gornik SG, Guo J, Hampl V, Hanawa Y, Haro-Contreras ER, Hehenberger E, Highfield A, Hirakawa Y, Hopes A, Howe CJ, Hu I, Ibañez J, Irwin NAT, Ishii Y, Janowicz NE, Jones AC, Kachale A, Fujimura-Kamada K, Kaur B, Kaye JZ, Kazana E, Keeling PJ, King N, Klobutcher LA, Lander N, Lassadi I, Li Z, Lin S, Lozano JC, Luan F, Maruyama S, Matute T, Miceli C, Minagawa J, Moosburner M, Najle SR, Nanjappa D, Nimmo IC, Noble L, Novák Vanclová AMG, Nowacki M, Nuñez I, Pain A, Piersanti A, Pucciarelli S, Pyrih J, Rest JS, Rius M, Robertson D, Ruaud A, Ruiz-Trillo I, Sigg MA, Silver PA, Slamovits CH, Jason Smith G, Sprecher BN, Stern R, Swart EC, Tsaousis AD, Tsypin L, Turkewitz A, Turnšek J, Valach M, Vergé V, von Dassow P, von der Haar T, Waller RF, Wang L, Wen X, Wheeler G, Woods A, Zhang H, Mock T, Worden AZ, Lukeš J
PMID: 32296171

Proceedings of the National Academy of Sciences of the United States of America. 2019-11-19; 116.47: 23609-23617.

Reduction-dependent siderophore assimilation in a model pennate diatom

Coale TH, Moosburner M, Horák A, Oborník M, Barbeau KA, Allen AE
PMID: 31685631

Nature communications. 2019-10-07; 10.1: 4552.

Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom

Smith SR, Dupont CL, McCarthy JK, Broddrick JT, Oborník M, Horák A, Füssy Z, Cihlář J, Kleessen S, Zheng H, McCrow JP, Hixson KK, Araújo WL, Nunes-Nesi A, Fernie A, Nikoloski Z, Palsson BO, Allen AE
PMID: 31591397

Nature communications. 2019-08-08; 10.1: 3582.

Manganese and iron deficiency in Southern Ocean Phaeocystis antarctica populations revealed through taxon-specific protein indicators

Wu M, McCain JSP, Rowland E, Middag R, Sandgren M, Allen AE, Bertrand EM
PMID: 31395884

The New phytologist. 2019-05-01; 222.3: 1364-1379.

Cross-compartment metabolic coupling enables flexible photoprotective mechanisms in the diatom Phaeodactylum tricornutum

Broddrick JT, Du N, Smith SR, Tsuji Y, Jallet D, Ware MA, Peers G, Matsuda Y, Dupont CL, Mitchell BG, Palsson BO, Allen AE
PMID: 30636322

Science (New York, N.Y.). 2018-09-28; 361.6409: 1356-1358.

Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom

Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Oborník M, Smith GJ, Hutchins DA, Allen AE, Moore BS
PMID: 30262498

The Plant cell. 2017-08-01; 29.8: 2047-2070.

Nitrate Reductase Knockout Uncouples Nitrate Transport from Nitrate Assimilation and Drives Repartitioning of Carbon Flux in a Model Pennate Diatom

McCarthy JK, McCarthy JK, Smith SR, McCrow JP, Tan M, Zheng H, Beeri K, Roth RA, Roth R, Lichtle C, Lichtle C, Goodenough U, Bowler C, Bowler CP, Dupont CL, Dupont CL, Allen AE
PMID: 28765511

Proceedings of the National Academy of Sciences of the United States of America. 2017-07-18; 114.29: E6015-E6024.

Diatom centromeres suggest a mechanism for nuclear DNA acquisition

Diner RE, Noddings CM, Lian NC, Kang AK, McQuaid JB, Jablanovic J, Espinoza JL, Nguyen NA, Anzelmatti MA, Jansson J, Bielinski VA, Karas BJ, Dupont CL, Allen AE, Weyman PD
PMID: 28673987

Frontiers in microbiology. 2017-05-30; 8.949.

Nutrient Stoichiometry Shapes Microbial Community Structure in an Evaporitic Shallow Pond

Lee ZM, Poret-Peterson AT, Siefert JL, Kaul D, Moustafa A, Allen AE, Dupont CL, Eguiarte LE, Souza V, Elser JJ
PMID: 28611750

PLoS genetics. 2017-03-29; 13.3: e1006688.

Correction: Transcriptional Orchestration of the Global Cellular Response of a Model Pennate Diatom to Diel Light Cycling under Iron Limitation

Smith SR, Gillard JT, Kustka AB, McCrow JP, Badger JH, Zheng H, New AM, Dupont CL, Obata T, Fernie AR, Allen AE
PMID: 28355217

Nature reviews. Microbiology. 2017-01-01; 15.1: 6-20.

Probing the evolution, ecology and physiology of marine protists using transcriptomics

Caron DA, Alexander H, Allen AE, Archibald JM, Armbrust EV, Bachy C, Bell CJ, Bharti A, Dyhrman ST, Guida SM, Heidelberg KB, Kaye JZ, Metzner J, Smith SR, Worden AZ
PMID: 27867198

PLoS genetics. 2016-12-01; 12.12: e1006490.

Transcriptional Orchestration of the Global Cellular Response of a Model Pennate Diatom to Diel Light Cycling under Iron Limitation

Smith SR, Gillard JT, Kustka AB, McCrow JP, Badger JH, Zheng H, New AM, Dupont CL, Obata T, Fernie AR, Allen AE
PMID: 27973599

Frontiers in microbiology. 2016-07-06; 7.1043.

Diversity and Expression of Bacterial Metacaspases in an Aquatic Ecosystem

Asplund-Samuelsson J, Sundh J, Dupont CL, Allen AE, McCrow JP, Celepli NA, Bergman B, Ininbergs K, Ekman M
PMID: 27458440

Frontiers in microbiology. 2016-06-09; 7.880.

Genetic Manipulation of Competition for Nitrate between Heterotrophic Bacteria and Diatoms

Diner RE, Schwenck SM, McCrow JP, Zheng H, Allen AE
PMID: 27375600

The New phytologist. 2016-05-01; 210.3: 890-904.

Transcript level coordination of carbon pathways during silicon starvation-induced lipid accumulation in the diatom Thalassiosira pseudonana

Smith SR, Glé C, Abbriano RM, Traller JC, Davis A, Trentacoste E, Vernet M, Allen AE, Hildebrand M
PMID: 26844818

PloS one. 2016-01-01; 11.3: e0160929.

Patterns of Transcript Abundance of Eukaryotic Biogeochemically-Relevant Genes in the Amazon River Plume

Zielinski BL, Allen AE, Carpenter EJ, Coles VJ, Crump BC, Doherty M, Foster RA, Goes JI, Gomes HR, Hood RR, McCrow JP, Montoya JP, Moustafa A, Satinsky BM, Sharma S, Smith CB, Yager PL, Paul JH
PMID: 27598790

Biotechnology for biofuels. 2016-01-01; 9.258.

Genome and methylome of the oleaginous diatom Cyclotella cryptica reveal genetic flexibility toward a high lipid phenotype

Traller JC, Cokus SJ, Lopez DA, Gaidarenko O, Smith SR, McCrow JP, Gallaher SD, Podell S, Thompson M, Cook O, Morselli M, Jaroszewicz A, Allen EE, Allen AE, Merchant SS, Pellegrini M, Hildebrand M
PMID: 27933100

The ISME journal. 2015-05-01; 9.5: 1076-92.

Genomes and gene expression across light and productivity gradients in eastern subtropical Pacific microbial communities

Dupont CL, McCrow JP, Valas R, Moustafa A, Walworth N, Goodenough U, Roth R, Hogle SL, Bai J, Johnson ZI, Mann E, Palenik B, Barbeau KA, Venter JC, Allen AE
PMID: 25333462

Nature communications. 2015-04-21; 6.6925.

Designer diatom episomes delivered by bacterial conjugation

Karas BJ, Diner RE, Lefebvre SC, McQuaid J, Phillips AP, Noddings CM, Brunson JK, Valas RE, Deerinck TJ, Jablanovic J, Gillard JT, Beeri K, Ellisman MH, Glass JI, Hutchison CA, Smith HO, Venter JC, Allen AE, Dupont CL, Weyman PD
PMID: 25897682

Current biology : CB. 2015-02-02; 25.3: 364-71.

A novel protein, ubiquitous in marine phytoplankton, concentrates iron at the cell surface and facilitates uptake

Morrissey J, Sutak R, Paz-Yepes J, Tanaka A, Moustafa A, Veluchamy A, Thomas Y, Botebol H, Bouget FY, McQuaid JB, Tirichine L, Allen AE, Lesuisse E, Bowler C
PMID: 25557662

Molecular phylogenetics and evolution. 2014-02-01; 71.36-40.

Massive difference in synonymous substitution rates among mitochondrial, plastid, and nuclear genes of Phaeocystis algae

Smith DR, Arrigo KR, Alderkamp AC, Allen AE
PMID: 24216019

Journal of biological engineering. 2013-12-10; 7.1: 30.

Assembly of eukaryotic algal chromosomes in yeast

Karas BJ, Molparia B, Jablanovic J, Hermann WJ, Lin YC, Dupont CL, Tagwerker C, Yonemoto IT, Noskov VN, Chuang RY, Allen AE, Glass JI, Hutchison CA, Smith HO, Venter JC, Weyman PD
PMID: 24325901

Current opinion in microbiology. 2013-10-01; 16.5: 605-17.

Lineage specific gene family enrichment at the microscale in marine systems

Allen AE, Allen LZ, McCrow JP
PMID: 24377115

Proceedings of the National Academy of Sciences of the United States of America. 2013-06-25; 110.26: E2390-9.

Candidate phylum TM6 genome recovered from a hospital sink biofilm provides genomic insights into this uncultivated phylum

McLean JS, Lombardo MJ, Badger JH, Edlund A, Novotny M, Yee-Greenbaum J, Vyahhi N, Hall AP, Yang Y, Dupont CL, Ziegler MG, Chitsaz H, Allen AE, Yooseph S, Tesler G, Pevzner PA, Friedman RM, Nealson KH, Venter JC, Lasken RS
PMID: 23754396

Frontiers in microbiology. 2013-05-30; 4.120.

Contrasting genomic properties of free-living and particle-attached microbial assemblages within a coastal ecosystem

Smith MW, Zeigler Allen L, Allen AE, Herfort L, Simon HM
PMID: 23750156

The New phytologist. 2013-04-01; 198.2: 398-407.

Transcriptomic analysis of metabolic function in the giant kelp, Macrocystis pyrifera, across depth and season

Konotchick T, Dupont CL, Valas RE, Badger JH, Allen AE
PMID: 23488966

Nature communications. 2013-01-01; 4.2091.

Insights into the role of DNA methylation in diatoms by genome-wide profiling in Phaeodactylum tricornutum

Veluchamy A, Lin X, Maumus F, Rivarola M, Bhavsar J, Creasy T, O'Brien K, Sengamalay NA, Tallon LJ, Smith AD, Rayko E, Ahmed I, Le Crom S, Farrant GK, Sgro JY, Olson SA, Bondurant SS, Allen AE, Allen A, Rabinowicz PD, Sussman MR, Bowler C, Tirichine L
PMID: 23820484

BMC genomics. 2012-09-20; 13.499.

Whole transcriptome analysis of the silicon response of the diatom Thalassiosira pseudonana

Shrestha RP, Tesson B, Norden-Krichmar T, Federowicz S, Hildebrand M, Allen AE
PMID: 22994549

Molecular systems biology. 2012-07-17; 8.595.

Global biogeography of SAR11 marine bacteria

Brown MV, Lauro FM, DeMaere MZ, Muir L, Wilkins D, Thomas T, Riddle MJ, Fuhrman JA, Andrews-Pfannkoch C, Hoffman JM, McQuaid JB, Allen A, Rintoul SR, Cavicchioli R
PMID: 22806143

The ISME journal. 2012-07-01; 6.7: 1403-14.

Influence of nutrients and currents on the genomic composition of microbes across an upwelling mosaic

Zeigler Allen L, Allen EE, Badger JH, McCrow JP, Paulsen IT, Elbourne LD, Thiagarajan M, Rusch DB, Nealson KH, Williamson SJ, Venter JC, Allen AE
PMID: 22278668

Trends in plant science. 2012-07-01; 17.7: 395-403.

Leveraging metabolomics for functional investigations in sequenced marine diatoms

Fernie AR, Obata T, Allen AE, Araújo WL, Bowler C
PMID: 22465020

Proceedings of the National Academy of Sciences of the United States of America. 2012-06-26; 109.26: E1762-71.

Influence of cobalamin scarcity on diatom molecular physiology and identification of a cobalamin acquisition protein

Bertrand EM, Allen AE, Dupont CL, Norden-Krichmar TM, Bai J, Valas RE, Saito MA
PMID: 22652568

Proceedings of the National Academy of Sciences of the United States of America. 2012-02-07; 109.6: E317-25.

Comparative metatranscriptomics identifies molecular bases for the physiological responses of phytoplankton to varying iron availability

Marchetti A, Schruth DM, Durkin CA, Parker MS, Kodner RB, Berthiaume CT, Morales R, Allen AE, Armbrust EV
PMID: 22308424

Molecular biology and evolution. 2012-01-01; 29.1: 367-79.

Evolution and functional diversification of fructose bisphosphate aldolase genes in photosynthetic marine diatoms

Allen AE, Moustafa A, Montsant A, Eckert A, Kroth PG, Bowler C
PMID: 21903677

Frontiers in microbiology. 2012-01-01; 3.375.

Influence of vitamin B auxotrophy on nitrogen metabolism in eukaryotic phytoplankton

Bertrand EM, Allen AE
PMID: 23091473

Photosynthesis research. 2011-09-01; 109.1-3: 205-21.

Localization of putative carbonic anhydrases in two marine diatoms, Phaeodactylum tricornutum and Thalassiosira pseudonana

Tachibana M, Allen AE, Kikutani S, Endo Y, Bowler C, Matsuda Y
PMID: 21365259

PloS one. 2011-08-12; 6.8: e22870.

Characterization of the small RNA transcriptome of the diatom, Thalassiosira pseudonana

Norden-Krichmar TM, Allen AE, Gaasterland T, Hildebrand M
PMID: 21857960

Nature. 2011-05-12; 473.7346: 203-7.

Evolution and metabolic significance of the urea cycle in photosynthetic diatoms

Allen AE, Dupont CL, Oborník M, Horák A, Nunes-Nesi A, McCrow JP, Zheng H, Johnson DA, Hu H, Fernie AR, Bowler C
PMID: 21562560

Proceedings of the National Academy of Sciences of the United States of America. 2011-03-08; 108.10: 3830-7.

Efficiency of the CO2-concentrating mechanism of diatoms

Hopkinson BM, Dupont CL, Allen AE, Morel FM
PMID: 21321195

Nature. 2010-11-04; 468.7320: 60-6.

Genomic and functional adaptation in surface ocean planktonic prokaryotes

Yooseph S, Nealson KH, Rusch DB, McCrow JP, Dupont CL, Kim M, Johnson J, Montgomery R, Ferriera S, Beeson K, Williamson SJ, Tovchigrechko A, Allen AE, Zeigler LA, Sutton G, Eisenstadt E, Rogers YH, Friedman R, Frazier M, Venter JC
PMID: 21048761

Current opinion in microbiology. 2010-10-01; 13.5: 652-60.

The voyage of the microbial eukaryote

Worden AZ, Allen AE
PMID: 20832353

Genome biology. 2010-08-25; 11.8: R85.

Digital expression profiling of novel diatom transcripts provides insight into their biological functions

Maheswari U, Jabbari K, Petit JL, Porcel BM, Allen AE, Cadoret JP, De Martino A, Heijde M, Kaas R, La Roche J, Lopez PJ, Martin-Jézéquel V, Meichenin A, Mock T, Schnitzler Parker M, Vardi A, Armbrust EV, Weissenbach J, Katinka M, Bowler C
PMID: 20738856

Proceedings of the National Academy of Sciences of the United States of America. 2010-08-17; 107.33: 14679-84.

Targeted metagenomics and ecology of globally important uncultured eukaryotic phytoplankton

Cuvelier ML, Allen AE, Monier A, McCrow JP, Messié M, Tringe SG, Woyke T, Welsh RM, Ishoey T, Lee JH, Binder BJ, Dupont CL, Latasa M, Guigand C, Buck KR, Hilton J, Thiagarajan M, Caler E, Read B, Lasken RS, Chavez FP, Worden AZ
PMID: 20668244

Nature. 2010-06-03; 465.7298: 617-21.

The Ectocarpus genome and the independent evolution of multicellularity in brown algae

Cock JM, Sterck L, Rouzé P, Scornet D, Allen AE, Amoutzias G, Anthouard V, Artiguenave F, Aury JM, Badger JH, Beszteri B, Billiau K, Bonnet E, Bothwell JH, Bowler C, Boyen C, Brownlee C, Carrano CJ, Charrier B, Cho GY, Coelho SM, Collén J, Corre E, Da Silva C, Delage L, Delaroque N, Dittami SM, Doulbeau S, Elias M, Farnham G, Gachon CM, Gschloessl B, Heesch S, Jabbari K, Jubin C, Kawai H, Kimura K, Kloareg B, Küpper FC, Lang D, Le Bail A, Leblanc C, Lerouge P, Lohr M, Lopez PJ, Martens C, Maumus F, Michel G, Miranda-Saavedra D, Morales J, Moreau H, Motomura T, Nagasato C, Napoli CA, Nelson DR, Nyvall-Collén P, Peters AF, Pommier C, Potin P, Poulain J, Quesneville H, Read B, Rensing SA, Ritter A, Rousvoal S, Samanta M, Samson G, Schroeder DC, Ségurens B, Strittmatter M, Tonon T, Tregear JW, Valentin K, von Dassow P, Yamagishi T, Van de Peer Y, Wincker P
PMID: 20520714

Science (New York, N.Y.). 2009-04-10; 324.5924: 268-72.

Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas

Worden AZ, Lee JH, Mock T, Rouzé P, Simmons MP, Aerts AL, Allen AE, Cuvelier ML, Derelle E, Everett MV, Foulon E, Grimwood J, Gundlach H, Henrissat B, Napoli C, McDonald SM, Parker MS, Rombauts S, Salamov A, von Dassow P, Badger JH, Coutinho PM, Demir E, Dubchak I, Gentemann C, Eikrem W, Gready JE, John U, Lanier W, Lindquist EA, Lucas S, Mayer KF, Moreau H, Not F, Otillar R, Panaud O, Pangilinan J, Paulsen I, Piegu B, Poliakov A, Robbens S, Schmutz J, Toulza E, Wyss T, Zelensky A, Zhou K, Armbrust EV, Bhattacharya D, Goodenough UW, Van de Peer Y, Grigoriev IV
PMID: 19359590

Current opinion in plant biology. 2006-06-01; 9.3: 264-73.

An ecological and evolutionary context for integrated nitrogen metabolism and related signaling pathways in marine diatoms

Allen AE, Vardi A, Bowler C
PMID: 16603409

Science (New York, N.Y.). 2004-10-01; 306.5693: 79-86.

The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism

Armbrust EV, Berges JA, Bowler C, Green BR, Martinez D, Putnam NH, Zhou S, Allen AE, Apt KE, Bechner M, Brzezinski MA, Chaal BK, Chiovitti A, Davis AK, Demarest MS, Detter JC, Glavina T, Goodstein D, Hadi MZ, Hellsten U, Hildebrand M, Jenkins BD, Jurka J, Kapitonov VV, Kröger N, Lau WW, Lane TW, Larimer FW, Lippmeier JC, Lucas S, Medina M, Montsant A, Obornik M, Parker MS, Palenik B, Pazour GJ, Richardson PM, Rynearson TA, Saito MA, Schwartz DC, Thamatrakoln K, Valentin K, Vardi A, Wilkerson FP, Rokhsar DS
PMID: 15459382

Projects

Team

Ariel Rabines

Research Associate III

Anne Schulberg

Laboratory Assistant

Hong Zheng, MS

Research Associate IV

Video

Diatoms Have Found a Way to Pirate Bacterial Iron Sources
Domoic Acid Decoded: Scientists Discover Genetic Basis for How Harmful Algal Blooms Become Toxic

News

12-Sep-2025
Press Release

Unveiling the secrets of an adaptable, ubiquitous ocean algae

Its DNA gives it broad range and critical importance in the current and future health of our oceans

19-Sep-2024
Press Release

Scientists discover molecular predictors of toxic algal blooms that pose health risk, ecological and economic harm

Genes in the algae Pseudo-nitzschia genus have been identified that act as a warning beacon for a dangerous neurotoxin

21-May-2024
Collaborator Release

Phytoplankton Genetically Sequenced at Sea for the First Time

Viking’s Initiative with UC San Diego’s Scripps Institution of Oceanography and J. Craig Venter Institute Aims to Provide Better Understanding of the “World’s Lungs”

10-Nov-2023
Press Release

Coastal upwelling regions threatened by increased ocean acidification

Increased acidification shown to limit iron availability, a critical element for the survival of phytoplankton, the foundation of the oceanic food web

04-May-2022
Collaborator Release

Scientists announce comprehensive regional diagnostic of microbial ocean life using DNA testing

Large-scale ‘metabarcoding’ methods could revolutionize how society understands forces that drive seafood supply, planet’s ability to remove greenhouse gases

26-Jul-2021
Press Release

Climate change and iron availability may drastically alter algae blooms in the Southern Ocean, trapping vast nutrients

Shifts in diatom population may have profound effects on global nutrient distribution and carbon cycling

18-Mar-2021
Press Release

Scientists map how iron, a critical mineral for survival, is processed by algae, a cornerstone of the ocean food web

Nearly forty proteins identified in the intracellular process, helping to build a conceptual overview of how iron is allocated within diatom cells

27-Sep-2018
Press Release

Domoic Acid Decoded: Scientists Discover Genetic Basis for How Harmful Algal Blooms Become Toxic

Research into gene function in microalgae helps determine how toxins are made in oceanic harmful algal blooms

16-Jul-2018
Media Advisory

Research Schooner Tara in San Diego Calls for Innovative Citizen Science and Oceanography 2.0

For in-depth evaluation of ocean health, biodiversity, and evolution