Microbiome
Both inside and out, our bodies harbor a huge array of bacteria and other micro-organisms collectively known as the human microbiome. Although bacteria are often thought to be dangerous, those that comprise the microbiome are essential for life. Our researchers are focused on understanding the delicate bacterial balance in the human body and how slight changes in that balance can either improve health or lead to devastating diseases.
Human Microbiome Project
Inflammation: Friend or Foe?
JCVI Associate Professor, Marcelo Freire, DDS, PhD, DMSc, continues to lead the field as he investigates the critical role the human microbiome plays in inflammation as the pathway to chronic disease.Differences Between Men and Women and the Role of Microbiome In Asthma Onset
Treating Oral Disease Through Better Understanding of the Oral Microbiome
Astronaut Microbiome
This project aims to understand how the extreme conditions of space travel affect the microbiome.
Bacterial Translocation and Changes in the Intestinal Microbiome in Mouse Models of Liver Disease
Impact of Diet on Human Immune Response, the Gut Microbiota, and Nutritional Status During Adaptation to Spaceflight
Forensics Microbiome Database
Help Take the Bite Out of Cancer
The goal is to find novel biomarkers to aid in prevention, diagnostics, and therapeutics of OSCC.
Improving Treatments for Urinary Tract Infections
Investigating membrane alterations as a mechanism of acid tolerance in caries-causing bacteria
The role of the oral microbiome and protection from acid damageRole of Talocins in Human Health
Saliva Proteome Database
The Human Salivary Proteome (HSP) Wiki as a public data portal for searching and retrieving custom-curated information about the proteome of human saliva.Revolutionizing the Future of Dental Care
Chronic Wound Microbiome
Center for Research on the Respiratory Microbiota of African Children (ReMAC)
Identifying Healthy Aging Biomarkers
This study aims to identify specific biomarkers that correlate with longevity and healthy aging using genomics and proteomics approaches.
Influenza: Host-Virus-Microbiome Interactions
Assembly-Enabled Genome-Resolved Examinations of Microbiomes
Alterations in the Nasal Microbiome During Human Influenza Infections
Role of Microbiome Diversity, Microbial Transcriptome and Host Gene Expression
Molecular and Microbiome Hallmarks of Acquired Immunity to Malaria
Effect of Xylitol Consumption on the Oral Microbiome
Gut Microbiome Sysbiosis in Childhood Acute Lymphoblastic Leukemia (ALL) Patients
Biomarker Discovery and Systems Biology for Types 1 and 2 Diabetes and Healthy Aging
Leonardo da Vinci DNA Project
This project utilizes genomics approaches to confirm the identity of the remains purported to be that of Leonardo da Vinci as well as to characterize the microbial population on aging artwork.
Relationship Between the Oral Microbiome and Caries Status of Young Twins
Genomics, Biomarkers and Mechanisms of Healing in Chronic Wounds
Utilize genomics approaches to identify the microbial composition and functional elements in non-healing and chronic wounds.
Proteomics for UTI diagnosis
Understanding host-pathogen interactions is critical when it comes to improving diagnostic approaches to urinary tract infections.
Genomics and Proteomics Approaches to T1D
This study addresses the complex interactions between the host and environmental factors as they relate to the development of Type I Diabetes (T1D).
Human Microbiome Project
The Human Microbiome Project involves characterizing human microbial isolates using whole genome shotgun sequencing.
The Ferret Upper Respiratory Microbiome
Asymptomatic Bacteriuria: Microbiome and Metaproteome
We use genomics approaches to detect the presence of bacteria with known inflammatory responses in asymptomatic patients.
Zoo in You Traveling Exhibition
Our bodies are home to trillions of bacteria. This project provides an education resource to middle and high school aged children who are interested in science and medicine.
Uncovering Role of Vaginal Microbiome and Connection to HPV Infection and Cervical Cancer
Understanding Dissemination Routes of Antibiotic Resistance During Early Life
Improving Non-Invasive Diagnostic Tests Predictive of Oral Helicobacter pylori Infection
Systems Biology for Molecular Analysis of Tuberculosis in Ethiopia
Microbiome and Host Response Signatures for Pneumonia Among Lung Transplant Recipients
Human Hair Microbiota
Understanding Biofilm Formation in Urethral Catheters
Toward Re-Programming the Gut Microbiome
The Nasopharynx Microbiome and Pneumococcal Vaccination in Filipino and South African Infants
Nasopharyngeal Microbiome and Respiratory Disease in African Children
Gut Microbiome-Based Metagenomic Signature for Detection of Advanced Fibrosis in Nonalcoholic Fatty Liver Disease
Progression of Esophageal Cancer
Searching for New Pathogens in Travelers’ Diarrhea
Transmission Kinetics of RSV Infection
Skin Microbiome and Psoriasis
TEDDY Infectious Agents
In this study, we propose to investigate the Prokaryotic species associated with the gut microbiome using whole genome shotgun metagenomic sequencing of stool samples via Solexa sequencing technology.
Vaginal Microbiome Project
A metagenomics approach to understanding the relationship between the vaginal microbiome, bacterial vaginosis, vaginal health and preterm birth.