Microbiome

Both inside and out, our bodies harbor a huge array of bacteria and other micro-organisms collectively known as the human microbiome.  Although bacteria are often thought to be dangerous, those that comprise the microbiome are essential for life. Our researchers are focused on understanding the delicate bacterial balance in the human body and how slight changes in that balance can either improve health or lead to devastating diseases.

Differences Between Men and Women and the Role of Microbiome In Asthma Onset

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Treating Oral Disease Through Better Understanding of the Oral Microbiome

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Astronaut Microbiome

This project aims to understand how the extreme conditions of space travel affect the microbiome. 

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Bacterial Translocation and Changes in the Intestinal Microbiome in Mouse Models of Liver Disease

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Impact of Diet on Human Immune Response, the Gut Microbiota, and Nutritional Status During Adaptation to Spaceflight

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Forensics Microbiome Database

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Help Take the Bite Out of Cancer

The goal is to find novel biomarkers to aid in prevention, diagnostics, and therapeutics of OSCC. 

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Improving Treatments for Urinary Tract Infections

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Role of Talocins in Human Health

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Saliva Proteome Database

The Human Salivary Proteome (HSP) Wiki as a public data portal for searching and retrieving custom-curated information about the proteome of human saliva.

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Revolutionizing the Future of Dental Care

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Chronic Wound Microbiome

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Center for Research on the Respiratory Microbiota of African Children (ReMAC)

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No More Needles!

Transforming the Treatment of Type 1 Diabetes

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Identifying Healthy Aging Biomarkers

This study aims to identify specific biomarkers that correlate with longevity and healthy aging using genomics and proteomics approaches.

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Influenza: Host-Virus-Microbiome Interactions

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Assembly-Enabled Genome-Resolved Examinations of Microbiomes

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Alterations in the Nasal Microbiome During Human Influenza Infections

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Role of Microbiome Diversity, Microbial Transcriptome and Host Gene Expression

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Molecular and Microbiome Hallmarks of Acquired Immunity to Malaria

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Effect of Xylitol Consumption on the Oral Microbiome

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Gut Microbiome Sysbiosis in Childhood Acute Lymphoblastic Leukemia (ALL) Patients

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Biomarker Discovery and Systems Biology for Types 1 and 2 Diabetes and Healthy Aging

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Leonardo da Vinci DNA Project

This project utilizes genomics approaches to confirm the identity of the remains purported to be that of Leonardo da Vinci as well as to characterize the microbial population on aging artwork.

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Relationship Between the Oral Microbiome and Caries Status of Young Twins

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Genomics, Biomarkers and Mechanisms of Healing in Chronic Wounds

Utilize genomics approaches to identify the microbial composition and functional elements in non-healing and chronic wounds.

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Proteomics for UTI diagnosis

Understanding host-pathogen interactions is critical when it comes to improving diagnostic approaches to urinary tract infections. 

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Genomics and Proteomics Approaches to T1D

This study addresses the complex interactions between the host and environmental factors as they relate to the development of Type I Diabetes (T1D). 

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Human Microbiome Project

The Human Microbiome Project involves characterizing human microbial isolates using whole genome shotgun sequencing.

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The Ferret Upper Respiratory Microbiome

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Asymptomatic Bacteriuria: Microbiome and Metaproteome

We use genomics approaches to detect the presence of bacteria with known inflammatory responses in asymptomatic patients. 

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26-May-2020
Press Release

Maintaining a Healthy Upper Respiratory Tract Microbiome May Help Prevent Secondary Infections in Influenza A Patients

An influenza-impacted upper respiratory tract microbiome may invite opportunistic bacterial pathogens

22-Aug-2019
Workshop Alert

JCVI/AADR Fall Focused Symposium

Integrating Omic Datasets Towards Translation

Uncovering Role of Vaginal Microbiome and Connection to HPV Infection and Cervical Cancer

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Understanding Dissemination Routes of Antibiotic Resistance During Early Life

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Improving Non-Invasive Diagnostic Tests Predictive of Oral Helicobacter pylori Infection

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Systems Biology for Molecular Analysis of Tuberculosis in Ethiopia

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Microbiome and Host Response Signatures for Pneumonia Among Lung Transplant Recipients

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Human Hair Microbiota

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Understanding Biofilm Formation in Urethral Catheters

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Toward Re-Programming the Gut Microbiome

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The Nasopharynx Microbiome and Pneumococcal Vaccination in Filipino and South African Infants

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Nasopharyngeal Microbiome and Respiratory Disease in African Children

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Gut Microbiome-Based Metagenomic Signature for Detection of Advanced Fibrosis in Nonalcoholic Fatty Liver Disease

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Progression of Esophageal Cancer

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Searching for New Pathogens in Travelers’ Diarrhea

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Transmission Kinetics of RSV Infection

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Skin Microbiome and Psoriasis

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TEDDY Infectious Agents

In this study, we propose to investigate the Prokaryotic species associated with the gut microbiome using whole genome shotgun metagenomic sequencing of stool samples via Solexa sequencing technology.

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Vaginal Microbiome Project

A metagenomics approach to understanding the relationship between the vaginal microbiome, bacterial vaginosis, vaginal health and preterm birth.

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Revealing Roles of Uncultivated Species in the Oral Microbiome

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Making a Quantum Leap in Plaque Research

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